Heartburn is a burning discomfort behind the breast bone. This is caused by reflux of stomach acid back into the oesophagus....

FAQ: Does omeprazole or similar drugs (known as PPIs) cause heart disease or dementia?

There have been some recent studies raising some possible long term problems with treatment using PPIs. These are association studies - that is they raise some concerns that need further study. There is no obvious mechanism for these drugs to affect the heart of brain - they act only on the gastric lining - but there is enough concern here to make sure that everyone on these drugs really does need to be on them longterm. Sometimes they can be started for "dubious" reasons and no-one makes the decision to stop

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